Marie-Josèphe Jude was born in Nice in 1968 from a French father and a sino-Vietnamese mother. She started to learn piano and harp in her home city before joining the Conservatoire de Paris, encouraged by G. Cziffra. She worked with Aldo Ciccolini (piano) and Jean Hubeau (chamber music), and was awarded a First Prize in piano and a concert license in harp at the Ecole Normale in Paris. She attended the third cycle in Jean-Claude Pennetier’s class. At that time, she regularly attended Maria Curcio-Diamand’s lessons in London.  In 1986, she met the composer Maurice  Ohana and became one of her favorite performers.  She was a finalist at the Clara Haskil Competition in 1989, and won the Victoire de la Musique in the category "New Talent" in 1995.

This is when her career developed internationally. She has appeared in concert halls and festivals all over the world, from Montpellier to Bath, from the Roque d’Anthéron to Kuhmo, from Bagatelle to Locarno, from Colmar to Québec, from Nantes to Tokyo, and so on. 

She has played as a soloist under the baton of Frans Brüggen and Charles Dutoit, Emmanuel Krivine, François-Xavier Roth, Jean-Yves Ossonce, Arturo Tamayo, Klaus Weise, with orchestras such as the Orchestre de Paris, the Nice Philharmonic Orchestra, the National Orchestra of Bordeaux, the Orchestre National d’ïle de France, les Siècles, the BBC Scottish Orchestra, Basel Symphonic Orchestra, Philharmonic Orchestra of Luxembourg, the Brussels Philharmonic, and the MDR in Leipzig.

Marie-Josèphe Jude is also a fine chamber musician who plays with Henri Demarquette and Xavier Phillips (cello), Philippe Graffin and Jean-Marc Phillips (violin), Pascal Moraguès and Michel Portal (clarinet).  In 1997, she founded a piano duo with Jean-François Heisser. Additionally, she regularly plays with Michel Béroff and Claire Désert. She frequently participates in ballets with her brother Charles Jude, "danseur étoile," and director of the Bordeaux Ballet.

She has recorded many CDs for the label Lyrinx, featuring works by Brahms and Mendelssohn. Works of Jolivet for the Diapason d’Or,  as well as works by Clara Schumann, Dutilleux-Ohana, Beethoven, Chopin, as well as a combo of Ravel and Debussy with Michel Béroff (2015).

After 4 years of teaching at the Conservatoire National Supérieur in Lyon (2012-2016), she is now a teacher at the CNSM in Paris. In October 2017, she was appointed President of the Nice International Summer Academy.